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| Chen,Yong; Shi,Jian-Xin; Pan,Xu-Feng; Feng,Jian; Zhao,Heng. |
| Over the past three decades, mortality from lung cancer has sharply and continuously increased in China, ascending to the first cause of death among all types of cancer. The ability to identify the actual sequence of gene mutations may help doctors determine which mutations lead to precancerous lesions and which produce invasive carcinomas, especially using next-generation sequencing (NGS) technology. In this study, we analyzed the latest lung cancer data in the COSMIC database, in order to find genomic "hotspots" that are frequently mutated in human lung cancer genomes. The results revealed that the most frequently mutated lung cancer genes are EGFR, KRAS and TP53.In recent years, EGFR and KRAS lung cancer test kits have been utilized for detecting lung... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lung cancer; Next-generation sequencing; Somatic mutation kit; COSMIC. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000300022 |
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| Zhou,Wei; Lv,Tengfei; Chen,Yong; Hu,Jianfeng; Zhang,Qiang; Ren,Wanjun. |
| ABSTRACT To increase rice yield potential, field experiments were conducted in farmers’ paddies in 2011 and 2012 to evaluate the effects of different nitrogen applications on the yield and panicle components of three typical indica hybrid rice varieties in Sichuan Province. The number of grains per panicle resulting from late nitrogen application (LA) was 12 % greater than that obtained from traditional nitrogen application (TA); this increase was the main source of improvements in yield. The number of surviving and differentiated spikelets (NSS and NDiS) resulting from LA was significantly higher than that measured under TA, especially for the Fyou498 cultivar, where the NSS and NDiS increased by 15 % and 14 %, respectively. Compared with TA, the number... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Panicle; Grain number; Branch; Degenerated rate; Yield. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162017000200127 |
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